Bioinformatics-based analysis of nicotinamide adenine dinucleotide metabolism-related genes to predict immune status and prognosis for head and neck squamous cell carcinoma patients

Bioinformatics-based analysis of nicotinamide adenine dinucleotide metabolism-related genes to predict immune status and prognosis for head and neck squamous cell carcinoma patients

BackgroundPatients suffering from head and neck squamous cell carcinoma (HNSCC) have a high recurrence rate and poor prognosis. Nicotinamide adenine dinucleotide (NAD+) is crucial in the progression of the tumor. Currently, the specific role of NAD+ in HNSCC remains elusive.MethodsFirst, weighted ge...

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Bibliographic Details
Main Authors: Zhenjie Guan, Xinyu Gu, Lian Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
WGCNA analysis
prognostic modeling
head and neck squamous cell carcinoma
gene mutation
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1609175/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1609175/full

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