Thermogenic Adipocytes Promote M2 Macrophage Polarization through CNNM4‐Mediated Mg Secretion

Thermogenic Adipocytes Promote M2 Macrophage Polarization through CNNM4‐Mediated Mg Secretion

Abstract M2 macrophages promote adipose tissue thermogenesis which dissipates energy in the form of heat to combat obesity. However, the regulation of M2 macrophages by thermogenic adipocytes is unclear. Here, it is identified magnesium (Mg) as a thermogenic adipocyte‐secreted factor to promote M2 m...

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Bibliographic Details
Main Authors: Anke Zhang, Junkun Jiang, Chuan Zhang, Houshi Xu, Wenjing Yu, Zhen‐Ning Zhang, Ling Yuan, Zhangming Lu, Yuqing Deng, Haonan Fan, Chaoyou Fang, Xiaoyu Wang, Anwen Shao, Sheng Chen, Huaming Li, Jiahua Ni, Wenhui Wang, Xiaonong Zhang, Jianmin Zhang, Bing Luan
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
adipose tissue thermogenesis
M2 macrophage polarization
magnesium
obesity
Online Access:https://doi.org/10.1002/advs.202401140
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https://doi.org/10.1002/advs.202401140

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