Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages
IntroductionProphages play a crucial role in the genomic diversity of Acinetobacter baumannii, contributing to its pathogenicity and adaptation.MethodsIn this study, we induced and sequenced seven prophages from five isolates of A. baumannii. These were analyzed with 967 prophages identified from va...
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Frontiers Media S.A.
2025-01-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1522711/full |
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| author | Dafne Arellano-Maciel Juan Manuel Hurtado-Ramírez Laura Carolina Camelo-Valera Santiago Castillo-Ramírez Alejandro Reyes Gamaliel López-Leal |
| author_facet | Dafne Arellano-Maciel Juan Manuel Hurtado-Ramírez Laura Carolina Camelo-Valera Santiago Castillo-Ramírez Alejandro Reyes Gamaliel López-Leal |
| author_sort | Dafne Arellano-Maciel |
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| description | IntroductionProphages play a crucial role in the genomic diversity of Acinetobacter baumannii, contributing to its pathogenicity and adaptation.MethodsIn this study, we induced and sequenced seven prophages from five isolates of A. baumannii. These were analyzed with 967 prophages identified from various isolates worldwide, plus 21 genomes of other phages infecting A. baumannii previously reported in NCBI. To have an overview of the populations of the prophages infecting A. baumannii.ResultsOur analysis revealed 13 major prophage clusters within the analyzed A. baumannii isolates. Notably, prophages belonging to the Vieuvirus genus were the most prevalent. Specifically, Vieuvirus-related phages were frequently identified in isolates from Thailand, Mexico, China, and South Korea, which show the geographic prevalence of A. baumannii prophages.DiscussionThis study highlights the importance of considering geographic factors to fully understand prophage diversity and their significant role in the evolutionary dynamics of A. baumannii. |
| format | Article |
| id | doaj-art-6b698d7adf2f40f69b63619f111529b9 |
| institution | Kabale University |
| issn | 1664-302X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Microbiology |
| spelling | doaj-art-6b698d7adf2f40f69b63619f111529b92025-01-28T22:13:23ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2025-01-011610.3389/fmicb.2025.15227111522711Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophagesDafne Arellano-Maciel0Juan Manuel Hurtado-Ramírez1Laura Carolina Camelo-Valera2Santiago Castillo-Ramírez3Alejandro Reyes4Gamaliel López-Leal5Laboratorio de Biología Computacional y Virómica Integrativa, Centro de Investigación en Dinámica Celular, Universidad Autónoma del Estado de Morelos, Cuernavaca, MexicoInstituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, MexicoMcGill Centre for Microbiome Research, Department of Microbiology and Immunology, McGill University, Montreal, QC, CanadaPrograma de Genómica Evolutiva, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, MexicoGrupo de Biología Computacional y Ecología Microbiana, Departamento de Ciencias Biológicas, Universidad de los Andes, Bogotá, ColombiaLaboratorio de Biología Computacional y Virómica Integrativa, Centro de Investigación en Dinámica Celular, Universidad Autónoma del Estado de Morelos, Cuernavaca, MexicoIntroductionProphages play a crucial role in the genomic diversity of Acinetobacter baumannii, contributing to its pathogenicity and adaptation.MethodsIn this study, we induced and sequenced seven prophages from five isolates of A. baumannii. These were analyzed with 967 prophages identified from various isolates worldwide, plus 21 genomes of other phages infecting A. baumannii previously reported in NCBI. To have an overview of the populations of the prophages infecting A. baumannii.ResultsOur analysis revealed 13 major prophage clusters within the analyzed A. baumannii isolates. Notably, prophages belonging to the Vieuvirus genus were the most prevalent. Specifically, Vieuvirus-related phages were frequently identified in isolates from Thailand, Mexico, China, and South Korea, which show the geographic prevalence of A. baumannii prophages.DiscussionThis study highlights the importance of considering geographic factors to fully understand prophage diversity and their significant role in the evolutionary dynamics of A. baumannii.https://www.frontiersin.org/articles/10.3389/fmicb.2025.1522711/fullprophagesbacteriophagesAcinetobacter baumanniiVieuvirusphages |
| spellingShingle | Dafne Arellano-Maciel Juan Manuel Hurtado-Ramírez Laura Carolina Camelo-Valera Santiago Castillo-Ramírez Alejandro Reyes Gamaliel López-Leal Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages Frontiers in Microbiology prophages bacteriophages Acinetobacter baumannii Vieuvirus phages |
| title | Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages |
| title_full | Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages |
| title_fullStr | Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages |
| title_full_unstemmed | Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages |
| title_short | Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages |
| title_sort | geographic variation in abundance and diversity of acinetobacter baumannii vieuvirus bacteriophages |
| topic | prophages bacteriophages Acinetobacter baumannii Vieuvirus phages |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1522711/full |
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