Beware of <i>N</i>-Benzoyloxybenzamides
Following a High-Throughput Screening campaign to discover inhibitors of acid ceramidase, we report the novel and extremely potent covalent inhibitor, <b>1</b>. Following resynthesis and stability monitoring, we discovered that <b>1</b> is chemically unstable and reacts with...
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Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-10-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/29/21/5143 |
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