An SIS sex-structured influenza A model with positive case fatality in an open population with varying size

This work aims to study the role of sex disparities on the overall outcome of influenza A disease. Therefore, the classical Susceptible-Infected-Susceptible (SIS) endemic model was extended to include the impact of sex disparities on the overall dynamics of influenza A infection which spreads in an...

Full description

Saved in:
Bibliographic Details
Main Authors: Muntaser Safan, Bayan Humadi
Format: Article
Language:English
Published: AIMS Press 2024-08-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2024306
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832590818582462464
author Muntaser Safan
Bayan Humadi
author_facet Muntaser Safan
Bayan Humadi
author_sort Muntaser Safan
collection DOAJ
description This work aims to study the role of sex disparities on the overall outcome of influenza A disease. Therefore, the classical Susceptible-Infected-Susceptible (SIS) endemic model was extended to include the impact of sex disparities on the overall dynamics of influenza A infection which spreads in an open population with a varying size, and took the potential lethality of the infection. The model was mathematically analyzed, where the equilibrium and bifurcation analyses were established. The model was shown to undergo a backward bifurcation at $ \mathcal{R}_0 = 1 $, for certain range of the model parameters, where $ \mathcal{R}_0 $ is the basic reproduction number of the model. The asymptotic stability of the equilibria was numerically investigated, and the effective threshold was determined. The differences in susceptibility, transmissibility and case fatality (of females with respect to males) are shown to remarkably affect the disease outcomes. Simulations were performed to illustrate the theoretical results.
format Article
id doaj-art-6b33cdba15cd4a73a09872b3dba25852
institution Kabale University
issn 1551-0018
language English
publishDate 2024-08-01
publisher AIMS Press
record_format Article
series Mathematical Biosciences and Engineering
spelling doaj-art-6b33cdba15cd4a73a09872b3dba258522025-01-23T07:47:47ZengAIMS PressMathematical Biosciences and Engineering1551-00182024-08-012186975701110.3934/mbe.2024306An SIS sex-structured influenza A model with positive case fatality in an open population with varying sizeMuntaser Safan0Bayan Humadi1Mathematics Department, Faculty of Science, Umm Al-Qura University, Makkah 21955, KSAMathematics Department, Faculty of Science, Umm Al-Qura University, Makkah 21955, KSAThis work aims to study the role of sex disparities on the overall outcome of influenza A disease. Therefore, the classical Susceptible-Infected-Susceptible (SIS) endemic model was extended to include the impact of sex disparities on the overall dynamics of influenza A infection which spreads in an open population with a varying size, and took the potential lethality of the infection. The model was mathematically analyzed, where the equilibrium and bifurcation analyses were established. The model was shown to undergo a backward bifurcation at $ \mathcal{R}_0 = 1 $, for certain range of the model parameters, where $ \mathcal{R}_0 $ is the basic reproduction number of the model. The asymptotic stability of the equilibria was numerically investigated, and the effective threshold was determined. The differences in susceptibility, transmissibility and case fatality (of females with respect to males) are shown to remarkably affect the disease outcomes. Simulations were performed to illustrate the theoretical results.https://www.aimspress.com/article/doi/10.3934/mbe.2024306sis modelequilibriacase fatalitybackward bifurcationeffective thresholdsex and gender disparitiesinfluenza a
spellingShingle Muntaser Safan
Bayan Humadi
An SIS sex-structured influenza A model with positive case fatality in an open population with varying size
Mathematical Biosciences and Engineering
sis model
equilibria
case fatality
backward bifurcation
effective threshold
sex and gender disparities
influenza a
title An SIS sex-structured influenza A model with positive case fatality in an open population with varying size
title_full An SIS sex-structured influenza A model with positive case fatality in an open population with varying size
title_fullStr An SIS sex-structured influenza A model with positive case fatality in an open population with varying size
title_full_unstemmed An SIS sex-structured influenza A model with positive case fatality in an open population with varying size
title_short An SIS sex-structured influenza A model with positive case fatality in an open population with varying size
title_sort sis sex structured influenza a model with positive case fatality in an open population with varying size
topic sis model
equilibria
case fatality
backward bifurcation
effective threshold
sex and gender disparities
influenza a
url https://www.aimspress.com/article/doi/10.3934/mbe.2024306
work_keys_str_mv AT muntasersafan ansissexstructuredinfluenzaamodelwithpositivecasefatalityinanopenpopulationwithvaryingsize
AT bayanhumadi ansissexstructuredinfluenzaamodelwithpositivecasefatalityinanopenpopulationwithvaryingsize
AT muntasersafan sissexstructuredinfluenzaamodelwithpositivecasefatalityinanopenpopulationwithvaryingsize
AT bayanhumadi sissexstructuredinfluenzaamodelwithpositivecasefatalityinanopenpopulationwithvaryingsize