Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia

Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia

Thromboembolic events are common in patients with essential thrombocythemia (ET). However, the pathophysiological mechanisms underlying the increased thrombotic risk remain to be determined. Here, we perform the first phenotypical characterization of platelet expression using single-cell mass cytome...

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Main Authors: Veronika Dill, Kilian Kirmes, Jiaying Han, Melissa Klug, Marc Rosenbaum, Giacomo Viggiani, Moritz von Scheidt, Markus List, Peter Herhaus, Jürgen Ruland, Florian Bassermann, Karl-Ludwig Laugwitz, Katharina S. Götze, Philipp J. Jost, Stefanie Jilg, Conor J. Bloxham, Philip W.J. Raake, Isabell Bernlochner, Dario Bongiovanni
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Platelets
Subjects:
CyTOF
essential thrombocythemia
GPVI
mass cytometry
platelets
ET
Online Access:https://www.tandfonline.com/doi/10.1080/09537104.2024.2358244
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https://www.tandfonline.com/doi/10.1080/09537104.2024.2358244

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