Structural insights into thraustochytrid-specific lipases using alphafold to identify the role of GXSXG motif

Abstract Background Triacylglycerol lipases (E.C. 3.1.1.3) are serine hydrolases, universally present in animals, plants and microbes and are an integral part of lipid metabolism. They are industrially relevant enzymes that cleave ester bonds of triacylglycerides to release free fatty acids and glyc...

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Bibliographic Details
Main Authors: Iqra Mariam, Ulrika Rova, Paul Christakopoulos, Leonidas Matsakas, Alok Patel
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Biotechnology
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Online Access:https://doi.org/10.1186/s12896-025-00972-8
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