Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens

Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens

Background Enhancing antigen cross-presentation is essential for the development of a tumor neoantigen vaccine. One approach is to stimulate antigen-presenting cells (APCs) to uptake neoantigens. Mycobacterium tuberculosis (MTb) contains pathogen-associated molecular patterns (PAMPs) recognized by A...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jie Jiang, Feng-Ying Huang, Shu-Zhen Dai, Guang-Hong Tan, Ming-Hui Chen, Hengyu Chen, Wu-Ping Zheng, Ri-Hong Wu, Weijing Xie
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2025-02-01
Series:	Journal for ImmunoTherapy of Cancer
Online Access:	https://jitc.bmj.com/content/13/2/e010150.full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Neoantigen immunotherapy: a novel treatment for bladder cancer
by: Ruiyang Lv, et al.
Published: (2025-01-01)

Unveiling immunogenic characteristics and neoantigens in endometrial cancer with POLE hotspot mutations for improved immunotherapy
by: Jian Huang, et al.
Published: (2025-01-01)

Innate Immune Recognition of Mycobacterium tuberculosis
by: Johanneke Kleinnijenhuis, et al.
Published: (2011-01-01)

Therapy of genomic unstable solid tumours (WHO grade 3/4）in clinical stage III/IV using individualised neoantigen tumour peptides-INP trial (individualised neoantigen tumour peptides immunotherapy): study protocol for an open-label, non-randomised, prospective, single-arm trial
by: Ling Wang, et al.
Published: (2022-06-01)

The implementation of whole-genome sequencing for Mycobacterium tuberculosis in Vietnam
by: D.T. Huong, et al.
Published: (2024-07-01)

Immunological Impacts of Diabetes on the Susceptibility of Mycobacterium tuberculosis
by: Birhanu Ayelign, et al.
Published: (2019-01-01)

Mycobacterium tuberculosis: 2014 Clinical Trials in Review
by: Kevin B Laupland, et al.
Published: (2015-01-01)

Disseminated Mycobacterium Tuberculosis and IgA Nephropathy
by: Gordon Audley, et al.
Published: (2022-01-01)

Mathematical model for the growth of Mycobacterium tuberculosis in the granuloma
by: Eduardo Ibargüen-Mondragón, et al.
Published: (2018-03-01)

Identification of neoantigens derived from alternative splicing and RNA modification
by: Jiyeon Park, et al.
Published: (2019-08-01)

Diversity of Mycobacterium tuberculosis Complex Lineages Associated with Pulmonary Tuberculosis in Southwestern, Uganda
by: Lisa, Nkatha Micheni, et al.
Published: (2021)

Dynamic allostery in the peptide/MHC complex enables TCR neoantigen selectivity
by: Jiaqi Ma, et al.
Published: (2025-01-01)

Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection.
by: Jacques Augenstreich, et al.
Published: (2025-01-01)

Identification of Mycobacterium tuberculosis and its Drug Resistance by Targeted Nanopore Sequencing Technology
by: Chen Tang, et al.
Published: (2025-02-01)

Whole-genome sequencing reveals transmission pattern and drug resistance of Mycobacterium tuberculosis intra- or inter-hosts
by: Feng Ding, et al.
Published: (2025-01-01)

Poor efficacy of the combination of clarithromycin, amikacin, and cefoxitin against Mycobacterium abscessus in the hollow fiber infection model
by: Etienne Vignaud, et al.
Published: (2025-01-01)

Vitamin D in Early Childhood and the Effect on Immunity to Mycobacterium tuberculosis
by: Anna Jane Battersby, et al.
Published: (2012-01-01)

Abdominopelvic Tuberculosis Secondary to a Nontuberculous Mycobacterium in an Immunocompetent Patient
by: Beng Kwang Ng, et al.
Published: (2017-01-01)

Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis
by: Valerie F. A. March, et al.
Published: (2025-01-01)

In-depth Analysis of IS6110 Genomic Variability in the Mycobacterium tuberculosis Complex
by: Jessica Comín, et al.
Published: (2022-02-01)

Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee
by: Cinthujah Balachander, et al.
Published: (2024-01-01)

High-Temperature Performance and Multiscale Damage Mechanisms of Hollow Cellulose Fiber-Reinforced Concrete
by: Liping Guo, et al.
Published: (2016-01-01)

Effects of Bedaquiline on Antimicrobial Activity and Cytokine Secretion of Macrophages Infected with Multidrug-Resistant Mycobacterium tuberculosis Strains
by: Xia-Li Lyu, et al.
Published: (2022-01-01)

Axial Compressive Behavior of Glass Fiber-Reinforced Hollow Concrete Columns
by: Xiangyang Jian, et al.
Published: (2022-01-01)

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells
by: Jonathan Kevin Sia, et al.
Published: (2015-01-01)

Clinical and Mycobacterium tuberculosis strain characteristics of tuberculosis patients with diabetes mellitus in Changping District, Beijing, China
by: Xiaolong Cao, et al.
Published: (2025-01-01)

Is International Travel an Emerging Issue on Transmission of Beijing Lineage Mycobacterium tuberculosis?
by: Pavithra S. Madamarandawala, et al.
Published: (2020-01-01)

RAPID AND SPESIFIC DETECTION OF MYCOBACTERIUM TUBERCULOSIS USING POLYMERASE CHAIN REACTION
by: Anita Kurniati, et al.
Published: (2019-12-01)

Corrigendum: In-depth analysis of IS6110 genomic variability in the Mycobacterium tuberculosis complex
by: Jessica Comín, et al.
Published: (2025-01-01)

The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion
by: Maja Reimann, et al.
Published: (2025-01-01)

Modelling the human immune response mechanisms to mycobacterium tuberculosis infection in the lungs
by: Gesham Magombedze, et al.
Published: (2006-07-01)

Comparative growth kinetics and drug susceptibility of Mycobacterium tuberculosis lineages prevalent in Ethiopia: implications for tuberculosis treatment and management
by: Tesfaye Gebreyohannis Hailemariam, et al.
Published: (2025-02-01)

Difference in Antibody Responses to Mycobacterium tuberculosis Antigens in Japanese Tuberculosis Patients Infected with the Beijing/Non-Beijing Genotype
by: Jingge Zhao, et al.
Published: (2017-01-01)

The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis
by: Andreas Römpp, et al.
Published: (2025-01-01)

Mycobacterium tuberculosis and Dual M. tuberculosis/M. bovis Infection as the Cause of Tuberculosis in a Gorilla and a Lioness, Respectively, in Ibadan Zoo, Nigeria
by: Aina Adeogun, et al.
Published: (2016-01-01)

Development of the novel gene chip and restriction fragment length polymorphism (RFLP) methods for rapid detection of Mycobacterium tuberculosis complex in broth culture
by: Wen-Hung Wang, et al.
Published: (2025-02-01)

Molecular and Serological Detection of Mycobacterium tuberculosis in Dairy Cattle From Sylhet, Bangladesh
by: Md. Mukter Hossain, et al.
Published: (2024-01-01)

Vaccination with an Attenuated Ferritin Mutant Protects Mice against Virulent Mycobacterium tuberculosis
by: Selvakumar Subbian, et al.
Published: (2015-01-01)

Mutations in Mycobacterium tuberculosis Isolates with Discordant Results for Drug-Susceptibility Testing in Peru
by: L. Solari, et al.
Published: (2020-01-01)

γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
by: Serena Meraviglia, et al.
Published: (2011-01-01)