HFD aggravated the arthritis and atherosclerosis by altering the intestinal status and gut microbiota

Abstract Rheumatoid arthritis (RA) and cardiovascular disease (CVD) are both the chronic inflammatory disease. To investigate the influence of secondary atherosclerosis on arthritis mice, we treated the ApoE−/− mice with K/BxN serum and high fat diet (HFD), and subsequently assessed the phenotypes a...

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Main Authors: Na Shi, Shan Jiang, Yue Zhao, Yang Zhang, Xinwang Duan, Guo-bao Hong, Zhongshan Yang, Yuanyuan Duan, Haitao Niu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-024-01014-3
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