Characteristics and Outcomes of Patients with Acute Promyelocytic Leukemia: A Single-center Experience

Characteristics and Outcomes of Patients with Acute Promyelocytic Leukemia: A Single-center Experience

Aim: Acute promyelocytic leukemia (APL) is defined by the t(15;17) chromosomal translocation, resulting in the promyelocytic leukemia-retinoic acid receptor alpha fusion gene. The introduction of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has led to survival rates surpassing 90%. This...

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Bibliographic Details
Main Authors: Sema Seçilmiş, Burcu Aslan Candır, Ersin Bozan, Samet Yaman, Bahar Uncu Ulu, Tuğçe Nur Yiğenoğlu, Dicle İskender, Merih Kızıl Çakar
Format: Article
Language:English
Published: Galenos Publishing House 2025-08-01
Series:Acta Haematologica Oncologica Turcica
Subjects:
acute promyelocytic leukemia
all-trans retinoic acid
arsenic trioxide
treatment outcome
Online Access:https://www.actaoncologicaturcica.com/articles/characteristics-and-outcomes-of-patients-with-acute-promyelocytic-leukemia-a-single-center-experience/doi/ahot.galenos.2025.2025-6-1
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https://www.actaoncologicaturcica.com/articles/characteristics-and-outcomes-of-patients-with-acute-promyelocytic-leukemia-a-single-center-experience/doi/ahot.galenos.2025.2025-6-1

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