IL6/CCL2 from M2-polarized microglia promotes breast cancer brain metastasis and the reversal effect of β-elemene

IL6/CCL2 from M2-polarized microglia promotes breast cancer brain metastasis and the reversal effect of β-elemene

IntroductionBrain metastasis (BM) is the most common and serious complication of breast cancer (BC). There is significant interest in investigating the crosstalk between BC cells and immune cells. β-elemene is the main pharmacodynamic component of Curcumae Rhizoma, a traditional Chinese medicine tha...

Full description

Saved in:
Bibliographic Details
Main Authors: Qian Feng, Cai-Zhi Li, Yi-Hua Zou, Xue-Yu Wang, Xia Yang, Rong Zhang, Zhong-Qiu Liu, Rong-Rong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
breast cancer brain metastasis
M2 microglia
IL6 and CCL2 cytokines
IL6-STAT3 signaling pathway
β-elemene
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1547333/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2025.1547333/full

Similar Items