Carboxyl-containing quinazolines and related heterocycles as carriers of anti-inflammatory activity

Carboxyl-containing quinazolines and related heterocycles as carriers of anti-inflammatory activity

Active pharmaceutical ingredients whose structure combines aromatic or heterocyclic fragments with pharmacophore carboxylic group are widespread on pharmaceutical market. The isolation of COX-NSAIDs complexes and following X-ray studies allowed to explain the key role of pharmacophore carboxylic gro...

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Bibliographic Details
Main Authors: N. I. Krasovska, V V. Stavytskyi, I. S. Nosulenko, O. Yu. Voskoboinik, S. I. Kovalenko
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2022-02-01
Series:Zaporožskij Medicinskij Žurnal
Subjects:
quinazolines
triazoles
heterocyclic compounds
fused-ring
molecular docking simulation
computational prediction of drug-target interactions
anti-inflammatory agents
Online Access:http://zmj.zsmu.edu.ua/article/view/241286/250048
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http://zmj.zsmu.edu.ua/article/view/241286/250048

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