Selenium–Chondroitin Sulfate Nanoparticles Inhibit Angiogenesis by Regulating the VEGFR2-Mediated PI3K/Akt Pathway

Selenium–Chondroitin Sulfate Nanoparticles Inhibit Angiogenesis by Regulating the VEGFR2-Mediated PI3K/Akt Pathway

Chondroitin sulfate (CS), a class of glycosaminoglycans covalently attached to proteins to form proteoglycans, is widely distributed in the extracellular matrix and cell surface of animal tissues. In our previous study, CS was used as a template for the synthesis of seleno-chondroitin sulfate (SeCS)...

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Bibliographic Details
Main Authors: Xia Zheng, Xiaofei Liu, Zhuo Wang, Rui Li, Qiaoli Zhao, Bingbing Song, Kit-Leong Cheong, Jianping Chen, Saiyi Zhong
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Marine Drugs
Subjects:
selenium–chondroitin sulfate
human umbilical vein endothelial cells
chick embryo chorionic allantoic assay
angiogenesis
VEGFR2 protein
Online Access:https://www.mdpi.com/1660-3397/23/1/22
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