Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA

Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA

Bacterial contractile injection systems (CIS) are phage tail-like macromolecular complexes that mediate cell-cell interactions by injecting effector proteins into target cells. CIS from Streptomyces coelicolor (CISSc) are localized in the cytoplasm. Under stress, they induce cell death and impact th...

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Bibliographic Details
Main Authors: Bastien Casu, Joseph W Sallmen, Peter E Haas, Govind Chandra, Pavel Afanasyev, Jingwei Xu, Martin Pilhofer, Susan Schlimpert
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
Subjects:
bacterial development
phage tail-like structures
regulated cell death
multicellularity
Streptomyces
contractile injection systems
Online Access:https://elifesciences.org/articles/104064
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https://elifesciences.org/articles/104064

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