Luteolin, a common flavone in vegetables, acts as a hormetin possessing neurotrophic function: signaling mediated by inducing mitochondrial stress

Luteolin, a common flavone in vegetables, acts as a hormetin possessing neurotrophic function: signaling mediated by inducing mitochondrial stress

This study aims to uncover the hormetic process of luteolin, a common dietary flavone, in neuronal cells through its role in inducing mitochondrial stress. In rat pheochromocytoma PC12 cells, luteolin at low concentrations caused a mild and reversible loss of mitochondrial membrane potential (MMP),...

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Bibliographic Details
Main Authors: Alex Xiong Gao, Tracy Chenxi Xia, Maggie Suisui Guo, Gary Kawing Yuen, Kevin Qiyun Wu, Tina Tingxia Dong, Karl Wah-Keung Tsim
Format: Article
Language:English
Published: Tsinghua University Press 2025-02-01
Series:Food Science and Human Wellness
Subjects:
flavonoids
hormesis
mitochondrial membrane potential
autophagy
mitophagy
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250035
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https://www.sciopen.com/article/10.26599/FSHW.2024.9250035

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