Combining Vascular Targeting Agents with Radiation: An Effective Anti-Tumor Treatment but Associated with Radiation-Induced Systemic Toxicity

Combining Vascular Targeting Agents with Radiation: An Effective Anti-Tumor Treatment but Associated with Radiation-Induced Systemic Toxicity

This study investigated the effect of combining radiation with an angiogenesis inhibitor and vascular disrupting agent on tumor response and systemic toxicity. CDF1 mice with 200 mm<sup>3</sup> foot implanted C3H mammary carcinomas were treated with TNP-470 (100 mg/kg every second day fo...

Full description

Saved in:
Bibliographic Details
Main Authors: Miwako Nomura, Rumi Murata, Line Brøndum, Eva Ehrnrooth, Brita S. Sørensen, Michael R. Horsman
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Radiation
Subjects:
combretastatin A-4 phosphate (CA4P)
TNP-470
radiation
tumor growth inhibition
systemic toxicity
Online Access:https://www.mdpi.com/2673-592X/4/4/24
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2673-592X/4/4/24

Similar Items