Development and validation of an ARID1A-related immune genes risk model in evaluating prognosis and immune therapeutic efficacy for gastric cancer patients: a translational study

Development and validation of an ARID1A-related immune genes risk model in evaluating prognosis and immune therapeutic efficacy for gastric cancer patients: a translational study

BackgroundMutations in the ARID1A gene, an integral component of the SWI/SNF complex, are prevalent, affecting prognosis and immune response in several malignancies, including gastric cancer (GC). The aim of this study was to identify ARID1A mutation-associated immune genes to construct an ARID1A-re...

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Main Authors: Jiangtao Zhang, Jingting Li, Shangfeng Yang, Xiaoyan Tang, Chunze Wang, Jiaxing Lin, Qiancheng Chen, Hui Xu, Yuanyuan Ma, Xiaoling Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
ARID1A
gastric cancer
molecular docking
immune gene risk model
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1541491/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1541491/full

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