Circulating Hsp70: a tumor biomarker for lymph node metastases and early relapse in thoracic cancer

Circulating Hsp70: a tumor biomarker for lymph node metastases and early relapse in thoracic cancer

Abstract Background Heat shock protein 70 (Hsp70) which is frequently overexpressed in many different cancer types is also present on the plasma membrane of tumor but not normal cells. The intensity of membrane-expressed Hsp70 (mHsp70) is associated with disease progression and treatment resistance....

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Bibliographic Details
Main Authors: Dominik Lobinger, Nicholas Taylor, Verena Messner, Sophie Seier, Johannes Bodner, Erika Roberts, Ali Bashiri Dezfouli, Alan Graham Pockley, Seyer Safi, Gabriele Multhoff
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cancer
Subjects:
NSCLC
Extracellular Hsp70
Biomarker
Liquid biopsy
Immune-phenotype
Online Access:https://doi.org/10.1186/s12885-025-14725-5
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https://doi.org/10.1186/s12885-025-14725-5

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