Population pharmacokinetic study of colistin for dose optimization in patients with acute on chronic liver failure (ACLF) patients

Population pharmacokinetic study of colistin for dose optimization in patients with acute on chronic liver failure (ACLF) patients

Introduction: Acute on chronic liver failure (ACLF) is characterized by severe systemic inflammation and multiple organ failures, posing high mortality risks, particularly in cirrhotic patients. The complex alterations in drug distribution and elimination kinetics observed in ACLF and sepsis patient...

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Main Authors: Dr Ritika Bhandari, Prof. Nusrat Shafiq, Dr. Naveen Murali, Dr. Soumya Vij, Dr. Nipun Verma, Dr. Avaneesh Kumar Pandey, Prof. Vikram Prakash Gota, Dr. M Surulivel Rajan, Prof. Ajay Kumar Duseja, Prof. Samir Malhotra
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224007665
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