Evidence for a JAK2/STAT3 proinflammatory and vasculogenic mimicry interrelated molecular signature in adipocyte-derived mesenchymal stromal/stem cells

Abstract Background During obesity, the excessive accumulation of fat in tissue promotes dysregulated hormonal and cytokine homeostasis that triggers chronic inflammation, which is, in part, associated with an increased incidence of some cancers. This protumoral inflammatory environment is further e...

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Main Authors: Carolane Veilleux, Marie-Ève Roy, Alain Zgheib, Michel Desjarlais, Borhane Annabi
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-025-02298-6
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