Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization

Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization

BackgroundThis study investigates the role of CDH1 gene single nucleotide polymorphisms (SNPs), mRNA transcription levels, and E-cadherin protein localization in Helicobacter pylori (Hp)-associated gastric diseases and their contribution to gastric mucosal carcinogenesis.MethodsGastric mucosal sampl...

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Bibliographic Details
Main Authors: Yunbo Wu, Yunzhan Zhang, Yunkai Dai, Qi Luo, Shaoyang Lan, Xu Chen, Weijing Chen, Ruliu Li, Ling Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
E-caderin
CDH1
gastric cancer
SNP
Helicobacer pylori
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1590680/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1590680/full

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