Effects of different ventilatory settings on alveolar and pulmonary microvessel dimensions in pigs

Effects of different ventilatory settings on alveolar and pulmonary microvessel dimensions in pigs

Abstract Mechanical ventilation with high tidal volume (TV) or positive end-expiratory pressure (PEEP) may induce lung overinflation and increased pulmonary vascular resistance to flow. In 8 healthy mechanically ventilated pigs, we evaluated whether incident dark field (IDF) vital microscopy, applie...

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Main Authors: Elisa Damiani, Erika Casarotta, Caterina Di Bella, Margherita Galosi, Alessio Angorini, Federica Serino, Adolfo Maria Tambella, Fulvio Laus, Samuele Zuccari, Alessio Salvucci Salice, Roberta Domizi, Andrea Carsetti, Can Ince, Abele Donati
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Mechanical ventilation
Pulmonary microcirculation
Ventilation/perfusion matching
Incident dark field
Hand-held vital microscopy
Online Access:https://doi.org/10.1038/s41598-024-82244-7
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https://doi.org/10.1038/s41598-024-82244-7

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