DNA methylation patterns and predictive models for metabolic disease risk in offspring of gestational diabetes mellitus

DNA methylation patterns and predictive models for metabolic disease risk in offspring of gestational diabetes mellitus

Abstract Background Gestational diabetes mellitus (GDM) is a common pregnancy complication with far-reaching implications for maternal and offspring health, strongly tied to epigenetic modifications, particularly DNA methylation. However, the precise molecular mechanisms by which GDM increases long-...

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Bibliographic Details
Main Authors: Na Wang, Suping Li, Li Yang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Gestational diabetes mellitus
Epigenetics
Predictive modeling
Differentially methylated positions
Insulin signaling
AMPK activation
Online Access:https://doi.org/10.1186/s13098-025-01707-7
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https://doi.org/10.1186/s13098-025-01707-7

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