G6f-like is an ITAM-containing collagen receptor in thrombocytes.

Collagen activates mammalian platelets through a complex of the immunoglobulin (Ig) receptor GPVI and the Fc receptor γ-chain, which has an immunoreceptor tyrosine-based activation motif (ITAM). Cross-linking of GPVI mediates activation through the sequential activation of Src and Syk family kinases...

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Bibliographic Details
Main Authors: Craig E Hughes, Uvaraj P Radhakrishnan, Marie Lordkipanidzé, Stuart Egginton, Johannes M Dijkstra, Pudur Jagadeeswaran, Stephen P Watson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0052622&type=printable
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