A supercritical oil extract of Schisandra chinensis seeds ameliorates Huntington’s disease-like symptoms and neuropathology: the potential role of anti-oxidant and anti-inflammatory effects

A supercritical oil extract of Schisandra chinensis seeds ameliorates Huntington’s disease-like symptoms and neuropathology: the potential role of anti-oxidant and anti-inflammatory effects

BackgroundHuntington disease (HD), a neurodegenerative autosomal dominant disorder, is characterized by involuntary choreatic movements with cognitive and behavioral disturbances. Up to now, no therapeutic strategies are available to completely ameliorate the progression of HD. Schisandra chinensis...

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Bibliographic Details
Main Authors: Hyo-Sung Jo, Youn-Woo Lee, So-Ri Son, Dae Sik Jang, Tae Woo Kwon, Yujeong Ha, Sang-Kwan Moon, Min Soo Kim, Ik-Hyun Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
seed oil of Schisandra chinensis
Huntington’s disease-like symptoms
anti-inflammation
antioxidant
neuroprotection
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1471024/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1471024/full

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