FTO suppresses DNA repair by inhibiting PARP1

FTO suppresses DNA repair by inhibiting PARP1

Abstract Maintaining genomic integrity and faithful transmission of genetic information is essential for the survival and proliferation of cells and organisms. DNA damage, which threatens the integrity of the genome, is rapidly sensed and repaired by mechanisms collectively known as the DNA damage r...

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Main Authors: Tianyi Zhu, Jing Zhi Anson Tan, Lingrui Zhang, He Huang, Sooraj S. Das, Flora Cheng, Pranesh Padmanabhan, Mathew J. K. Jones, Mihwa Lee, Albert Lee, Jocelyn Widagdo, Victor Anggono
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58309-0
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https://doi.org/10.1038/s41467-025-58309-0

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