Spectral and coupling characteristics of somatosensory cortex and centromedian thalamus differentiate between pre- and inter-ictal 5–9 Hz oscillations in a genetic rat model of absence epilepsy

Spectral and coupling characteristics of somatosensory cortex and centromedian thalamus differentiate between pre- and inter-ictal 5–9 Hz oscillations in a genetic rat model of absence epilepsy

Spike-wave-discharges (SWD) are the electrophysiological hallmark of absence epilepsy. SWD are generated in the thalamo-cortical network and a seizure onset zone was identified in the somatosensory cortex (S1). We have shown before that inhibition of the centromedian thalamic nucleus (CM) in GAERS r...

Full description

Saved in:
Bibliographic Details
Main Authors: Eleni Nikalexi, Vladimir Maksimenko, Thomas Seidenbecher, Thomas Budde, Hans-Christian Pape, Annika Lüttjohann
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Neurobiology of Disease
Subjects:
Spike and wave discharges
GAERS
Somatosensory cortex
Centromedian thalamus
Network analysis
Evoked potentials
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124003796
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S0969996124003796

Similar Items