Low-intensity pulsed ultrasound inhibits chondrocyte senescence by inhibiting PI3K/AKT/mTOR signaling

Low-intensity pulsed ultrasound inhibits chondrocyte senescence by inhibiting PI3K/AKT/mTOR signaling

Cellular senescence is an important cause of age-related degenerative diseases, including osteoarthritis (OA). Chondrocyte senescence is crucial in OA onset and progression. As a non-invasive, safe, and widely used physical rehabilitation factor, the effect and mechanism of low intensity pulsed ultr...

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Bibliographic Details
Main Authors: Wang Han, Mengtong Guan, Bo Liao, Xiaoyu Han, Kaiting Li, Qing Chen, Xiya Guo, Yajuan Niu, Ying Zhu, Dingqun Bai
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2025-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Cellular senescence
Chondrocytes
Osteoarthritis
Ultrasonic waves
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2025000100630&tlng=en
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