8-Hydroxy-5-nitroquinoline as a C-nucleophilic reagent in the reaction of C, C-coupling with quinazoline

The first example of the reaction of 5-nitro-8-hydroxyquinoline as a C-nucleophile with quinazoline is described. As a result of the reaction of C, C-coupling, a stable σ-adduct containing the drug nitroxalin on a heterocyclic carrier was obtained. The structure of the resulting adduct was confirmed...

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Bibliographic Details
Main Authors: Yuri A. Azev, Olga S. Koptyaeva, Oleg S. Eltsov, Anton N. Tsmokalyuk, Tatyana A. Pospelova
Format: Article
Language:English
Published: Ural Federal University 2020-12-01
Series:Chimica Techno Acta
Subjects:
Online Access:https://chimicatechnoacta.ru/article/view/4768
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