Pan-cancer analysis reveals ASCC family promotes the cancer progression of lung adenocarcinoma

Pan-cancer analysis reveals ASCC family promotes the cancer progression of lung adenocarcinoma

Abstract The ASC-1 complex, consisting of TRIP4, ASCC1, ASCC2, and ASCC3, plays a pivotal role in regulating nuclear receptors and transcription factors that influence immunity, cellular proliferation, and apoptosis, and a multiomic analysis of ASCC1/2/3 was therefore performed to investigate its po...

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Bibliographic Details
Main Authors: Yimin Pan, Jun Tan, Changwu Wu, Chunbo Liu, Zheng Chen, Yongye Zhu, Fushu Luo, Qing Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
ASCC1/2/3
ASC-1 complex
Tumor biology
Immune regulation
Lung adenocarcinoma
Online Access:https://doi.org/10.1038/s41598-025-03946-0
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https://doi.org/10.1038/s41598-025-03946-0

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