Heterotypic spheroids as a strategy for 3D culture of cryopreserved primary human hepatocytes in stirred-tank systems
Primary human hepatocytes (PHHs) are the preferred cell source to address liver function. Despite originating from the native tissue, one of the bottlenecks when using primary material is the donor-to-donor variability. Cryopreserved PHHs offer a high number of cells from the same donor and standard...
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| Main Authors: | Francisca Arez, Lena Preiss, Isabella Ramella Gal, Sofia P. Rebelo, Lassina Badolo, Catarina Brito, Thomas Spangenberg, Paula M. Alves |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
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| Series: | SLAS Discovery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2472555225000036 |
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