Artemisinin synergizes with CCCP in autophagic cell death induction via ER stress in uveal melanoma

Summary: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, and it is associated with a poor prognosis due to the lack of effective targeted therapies. Artemisinin (ARS), a widely used antimalarial drug, has demonstrated anti-tumor effects in several types of cancer, in...

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Bibliographic Details
Main Authors: Minyue Xie, Xiang Gu, Zheng Zhao, Yu Hua, Qianru Wu, Yizhen Tang, Ai Zhuang, Shengfang Ge, Renbing Jia, Jie Yu, Jing Ruan, Xianqun Fan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225012337
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