Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection: a prospective, randomized, controlled, single-center, 24-month, open-label, parallel group trial

Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection: a prospective, randomized, controlled, single-center, 24-month, open-label, parallel group trial

Abstract Background Surgical resection is considered the most effective therapeutic method for pulmonary aspergilloma (PA), while the necessity of postoperative antifungal therapy remains controversial. Previous studies have several shortcomings such as retrospective design and inadequate follow-up...

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Main Authors: Jian Yang, Chan Liu, Jianxiong Li, Xianqiu Chen, Beibei Wang, Jing Zhang, Haifeng Wang, Deping Zhao, Yiming Zhou, Haomin Cai, Jin-fu Xu, Shuo Liang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Infectious Diseases
Subjects:
Pulmonary aspergilloma
Surgical resection
Voriconazole
Aspergillus recurrence
Side effect
Online Access:https://doi.org/10.1186/s12879-025-11267-w
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https://doi.org/10.1186/s12879-025-11267-w

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