Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults
Aim. The practical guidelines are intended for primary care physicians, general practitioners, paediatricians, gastroenterologists and general internists to advance the treatment and prevention of gastroenterological diseases in adults and children in therapies with probiotics, prebiotics, synbiotic...
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2021-06-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/578 |
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| author | V. T. Ivashkin I. V. Maev D. I. Abdulganieva S. A. Alekseenko A. V. Gorelov I. N. Zakharova O. Yu. Zolnikova N. Yu. Ivashkina N. V. Korochanskaya S. N. Mammayev E. A. Poluektova A. S. Trukhmanov D. V. Usenko Yu. P. Uspensky V. V. Tsukanov O. S. Shifrin I. V. Berezhnaya K. V. Ivashkin T. L. Lapina R. V. Maslennikov S. V. Nikolaeva N. G. Sugyan A. I. Ulyanin |
| author_facet | V. T. Ivashkin I. V. Maev D. I. Abdulganieva S. A. Alekseenko A. V. Gorelov I. N. Zakharova O. Yu. Zolnikova N. Yu. Ivashkina N. V. Korochanskaya S. N. Mammayev E. A. Poluektova A. S. Trukhmanov D. V. Usenko Yu. P. Uspensky V. V. Tsukanov O. S. Shifrin I. V. Berezhnaya K. V. Ivashkin T. L. Lapina R. V. Maslennikov S. V. Nikolaeva N. G. Sugyan A. I. Ulyanin |
| author_sort | V. T. Ivashkin |
| collection | DOAJ |
| description | Aim. The practical guidelines are intended for primary care physicians, general practitioners, paediatricians, gastroenterologists and general internists to advance the treatment and prevention of gastroenterological diseases in adults and children in therapies with probiotics, prebiotics, synbiotics and their enriched functional foods.Key points. Probiotics are live microorganisms that sustain health of the host when supplied in adequate amounts. Prebiotics include human-indigestible but accessible to gut microbiota substances expediting specific changes in the composition and/or activity of gastrointestinal microbiota that favour the host health. The mechanism of probiotic action comprises the quorum resistance maintenance, nutrient substrate metabolism and end metabolite recycling, macroorganism-sustaining substrate production, as well as the mediation of local and adaptive immune responses.The Russian Federation regulates market differently for biologically active food additives (BAFA), medicinal products (drugs) and functional food products (FFP). We overview the probiotic strains regulated in Russia as BAFAs, drugs and FFPs and provide recommendations on the use of these strains in treatment and prevention of gastroenterological diseases in children and adults.Conclusion. The clinical efficacy of probiotics, prebiotics, synbiotics and fortified functional foods depends on the prebiotic and strain properties and is verified in appropriate comparative clinical trials. Not all probiotics registered in Russia as BAFAs, drugs and FFPs have a strain identity, which provides no warranty of the clinical effect expected. The FFP legislation demands improved regulation mechanisms and control for therapeutic efficacy. |
| format | Article |
| id | doaj-art-694975bb6c7c4fe2930cd053448ab306 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2021-06-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-694975bb6c7c4fe2930cd053448ab3062025-02-10T16:14:36ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732021-06-01312659110.22416/1382-4376-2021-31-2-65-91424Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and AdultsV. T. Ivashkin0I. V. Maev1D. I. Abdulganieva2S. A. Alekseenko3A. V. Gorelov4I. N. Zakharova5O. Yu. Zolnikova6N. Yu. Ivashkina7N. V. Korochanskaya8S. N. Mammayev9E. A. Poluektova10A. S. Trukhmanov11D. V. Usenko12Yu. P. Uspensky13V. V. Tsukanov14O. S. Shifrin15I. V. Berezhnaya16K. V. Ivashkin17T. L. Lapina18R. V. Maslennikov19S. V. Nikolaeva20N. G. Sugyan21A. I. Ulyanin22Sechenov First Moscow State University (Sechenov University)Yevdokimov Moscow State University of Medicine and DentistryKazan State Medical UniversityFar-Eastern State Medical UniversitySechenov First Moscow State University (Sechenov University); Central Research Institute of EpidemiologyRussian Medical Academy of Continuous Professional EducationSechenov First Moscow State University (Sechenov University)Russian Medical Academy of Continuous Professional EducationKuban State Medical UniversityDagestan State Medical UniversitySechenov First Moscow State University (Sechenov University)Sechenov First Moscow State University (Sechenov University)Russian Medical Academy of Continuous Professional EducationSaint-Petersburg State Pediatric Medical UniversityResearch Institute for Medical Problems in the North — Division of Krasnoyarsk Scientific Centre of the Siberian Branch of the RASSechenov First Moscow State University (Sechenov University)Russian Medical Academy of Continuous Professional EducationSechenov First Moscow State University (Sechenov University)Sechenov First Moscow State University (Sechenov University)Sechenov First Moscow State University (Sechenov University)Central Research Institute of EpidemiologyRussian Medical Academy of Continuous Professional EducationSechenov First Moscow State University (Sechenov University)Aim. The practical guidelines are intended for primary care physicians, general practitioners, paediatricians, gastroenterologists and general internists to advance the treatment and prevention of gastroenterological diseases in adults and children in therapies with probiotics, prebiotics, synbiotics and their enriched functional foods.Key points. Probiotics are live microorganisms that sustain health of the host when supplied in adequate amounts. Prebiotics include human-indigestible but accessible to gut microbiota substances expediting specific changes in the composition and/or activity of gastrointestinal microbiota that favour the host health. The mechanism of probiotic action comprises the quorum resistance maintenance, nutrient substrate metabolism and end metabolite recycling, macroorganism-sustaining substrate production, as well as the mediation of local and adaptive immune responses.The Russian Federation regulates market differently for biologically active food additives (BAFA), medicinal products (drugs) and functional food products (FFP). We overview the probiotic strains regulated in Russia as BAFAs, drugs and FFPs and provide recommendations on the use of these strains in treatment and prevention of gastroenterological diseases in children and adults.Conclusion. The clinical efficacy of probiotics, prebiotics, synbiotics and fortified functional foods depends on the prebiotic and strain properties and is verified in appropriate comparative clinical trials. Not all probiotics registered in Russia as BAFAs, drugs and FFPs have a strain identity, which provides no warranty of the clinical effect expected. The FFP legislation demands improved regulation mechanisms and control for therapeutic efficacy.https://www.gastro-j.ru/jour/article/view/578probioticprobiotic strainprebioticsymbioticfunctional foodfunctional food ingredientacute diarrheaantibiotic-associated diarrhea<i>c. difficile</i>-associated disease<i>h. pylori</i> eradicationinflammatory bowel diseaseulcerative colitiscrohn’s diseasepouchitisirritable bowel syndromefunctional constipationfunctional dyspepsiadiarrhoea preventionhepatic encephalopathygastroenteritis |
| spellingShingle | V. T. Ivashkin I. V. Maev D. I. Abdulganieva S. A. Alekseenko A. V. Gorelov I. N. Zakharova O. Yu. Zolnikova N. Yu. Ivashkina N. V. Korochanskaya S. N. Mammayev E. A. Poluektova A. S. Trukhmanov D. V. Usenko Yu. P. Uspensky V. V. Tsukanov O. S. Shifrin I. V. Berezhnaya K. V. Ivashkin T. L. Lapina R. V. Maslennikov S. V. Nikolaeva N. G. Sugyan A. I. Ulyanin Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults Российский журнал гастроэнтерологии, гепатологии, колопроктологии probiotic probiotic strain prebiotic symbiotic functional food functional food ingredient acute diarrhea antibiotic-associated diarrhea <i>c. difficile</i>-associated disease <i>h. pylori</i> eradication inflammatory bowel disease ulcerative colitis crohn’s disease pouchitis irritable bowel syndrome functional constipation functional dyspepsia diarrhoea prevention hepatic encephalopathy gastroenteritis |
| title | Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults |
| title_full | Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults |
| title_fullStr | Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults |
| title_full_unstemmed | Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults |
| title_short | Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults |
| title_sort | practical recommendations of scientific society for the study of human microbiome and the russian gastroenterological association on use of probiotics prebiotics synbiotics and functional foods in treatment and prevention of gastroenterological diseases in children and adults |
| topic | probiotic probiotic strain prebiotic symbiotic functional food functional food ingredient acute diarrhea antibiotic-associated diarrhea <i>c. difficile</i>-associated disease <i>h. pylori</i> eradication inflammatory bowel disease ulcerative colitis crohn’s disease pouchitis irritable bowel syndrome functional constipation functional dyspepsia diarrhoea prevention hepatic encephalopathy gastroenteritis |
| url | https://www.gastro-j.ru/jour/article/view/578 |
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