Nonviral targeted mRNA delivery: principles, progresses, and challenges

Nonviral targeted mRNA delivery: principles, progresses, and challenges

Abstract Messenger RNA (mRNA) therapeutics have garnered considerable attention due to their remarkable efficacy in the treatment of various diseases. The COVID‐19 mRNA vaccine and RSV mRNA vaccine have been approved on the market. Due to the inherent nuclease‐instability and negative charge of mRNA...

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Main Authors: Xi He, Guohong Li, Letao Huang, Haixing Shi, Sha Zhong, Siyu Zhao, Xiangyu Jiao, Jinxiu Xin, Xiaoling Yin, Shengbin Liu, Zhongshan He, Mengran Guo, Chunli Yang, Zhaohui Jin, Jun Guo, Xiangrong Song
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:MedComm
Subjects:
delivery obstacles
mRNA therapeutics
nonviral delivery
targeted delivery systems
Online Access:https://doi.org/10.1002/mco2.70035
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https://doi.org/10.1002/mco2.70035

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