Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program.

Growth and starvation are considered opposite ends of a spectrum. To sustain growth, cells use coordinated gene expression programs and manage biomolecule supply in order to match the demands of metabolism and translation. Global growth programs complement increased ribosomal biogenesis with suffici...

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Bibliographic Details
Main Authors: Rajalakshmi Srinivasan, Adhish S Walvekar, Zeenat Rashida, Aswin Seshasayee, Sunil Laxman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Genetics
Online Access:https://europepmc.org/articles/pmc7773203?pdf=render
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