Detection and significance of HPV16 E5-specific productive transcripts in oropharyngeal carcinoma

Detection and significance of HPV16 E5-specific productive transcripts in oropharyngeal carcinoma

Abstract Background HPV16 is implicated in around 30% of oropharyngeal cancers (OPCs). HPV-associated OPCs generally show a better prognosis, but 20% deviate from this trend, indicating a need for better molecular profiling. HPV16-E5 is an oncoprotein encoded by an mRNA that undergoes extensive spli...

Full description

Saved in:
Bibliographic Details
Main Authors: Maria Gabriella Donà, Francesca Paolini, Maria Benevolo, Francesca Rollo, Elisabetta Merenda, Eugenia Giuliani, Flaminia Campo, Claudia Bonomo, Francesco Lorusso, Fabio Cecconi, Rita Antonelli, Ignazio La Mantia, Giuseppe D’Ermo, Renato Covello, Barbara Pichi, Raul Pellini, Antonio Carlos De Freitas, Andrew Sharabi, Aldo Venuti
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cancer
Subjects:
Oropharyngeal cancer (OPC)
HPV
E5 mRNA
Transcripts
HLA-I
EGFR
Online Access:https://doi.org/10.1186/s12885-025-14506-0
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12885-025-14506-0

Similar Items