Physicochemical profiling and ranking of parkinson’s disease drugs through QSPR and Fuzzy TOPSIS analysis

Physicochemical profiling and ranking of parkinson’s disease drugs through QSPR and Fuzzy TOPSIS analysis

Abstract Parkinson’s disease is a progressive neurological disorder characterized by the degeneration of the nervous system, leading to impaired motor and non-motor functions. Early symptoms include tremors, rigidity, and bradykinesia, with progressive deterioration over time. This study employs a m...

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Bibliographic Details
Main Authors: YuLan Chen, Abdul Rauf, Aqsa Shafique, Fairouz Tchier, Adnan Aslam, Keneni Abera Tola
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Fuzzy Topsis
Topological descriptors
Biochemistry
Human health
Linear regression
Online Access:https://doi.org/10.1038/s41598-025-99583-8
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https://doi.org/10.1038/s41598-025-99583-8

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