The Metabolite Indole‐3‐Acetic Acid of Bacteroides Ovatus Improves Atherosclerosis by Restoring the Polarisation Balance of M1/M2 Macrophages and Inhibiting Inflammation

The Metabolite Indole‐3‐Acetic Acid of Bacteroides Ovatus Improves Atherosclerosis by Restoring the Polarisation Balance of M1/M2 Macrophages and Inhibiting Inflammation

Abstract Emerging research has highlighted the significant role of the gut microbiota in atherosclerosis (AS), with microbiota‐targeted interventions offering promising therapeutic potential. A central component of this process is gut‐derived metabolites, which play a crucial role in mediating the d...

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Bibliographic Details
Main Authors: Wu Liu, Jingyu Wang, Heng Yang, Congcong Li, Wanqi Lan, Tingtao Chen, Yanhua Tang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
atherosclerosis
gut metabolites
gut microbiota
inflammation
macrophage polarisation
Online Access:https://doi.org/10.1002/advs.202413010
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https://doi.org/10.1002/advs.202413010

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