A GWAS of angiotensin-converting enzyme inhibitor-induced angioedema in a South African population

A GWAS of angiotensin-converting enzyme inhibitor-induced angioedema in a South African population

Background: Angiotensin-converting enzyme inhibitor–induced angioedema (AE-ACEI) is a life-threatening adverse event; globally, it is the most common cause of emergency presentations with angioedema. Several genome-wide association studies (GWASs) have found genomic associations with AE-ACEI. Howeve...

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Main Authors: Jacquiline W. Mugo, PhD, Cascia Day, Cert Allergy (Phys), Ananyo Choudhury, PhD, Maria Deetlefs, Dip Allergy (SA), Robert Freercks, MPhil, Sian Geraty, MMed, Angelica Panieri, MBChB, Christian Cotchobos, MBChB, Melissa Ribeiro, MBChB, Adelein Engelbrecht, MMed, Lisa K. Micklesfield, PhD, Michèle Ramsay, PhD, Sarah Pedretti, PhD, Jonny Peter, PhD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Angioedema
genome-wide association studies
angiotensin-converting enzyme inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325000657
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