The study of ECM hardness and mechanical pressure promoting TSCC progression by activating RET in a 4D culture system
This study developed a 4D dynamic culture model (a 3D hydrogel system integrated with time-dependent mechanical stimuli via magnetic nanoparticles) to simulate tongue movement and investigate the roles of ECM stiffness and mechanical pressure in tongue squamous cell carcinoma (TSCC) progression. The...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-10-01
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| Series: | Materials & Design |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S026412752501010X |
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