Diagnosis of deep vein thrombosis from γ-butylbetaine and l-carnitine in plasma and urine based on untargeted and targeted metabolomics

Diagnosis of deep vein thrombosis from γ-butylbetaine and l-carnitine in plasma and urine based on untargeted and targeted metabolomics

Abstract Deep vein thrombosis (DVT) is a significant contributor to the global disease burden. This study aimed to identify metabolic biomarkers to compensate for the limitation in specificity and singular nature of D-dimer test. UHPLC–MS was used to examine γ-butylbetaine and l-carnitine levels in...

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Bibliographic Details
Main Authors: Wenjie Zeng, Qitao Wang, Xin Li, Zhen Wang, Junyu Chi, Zhicong Yang, Jingqi Li, Yang yang Gao, Ming Qu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Deep vein thrombosis
Metabolomics
Biomarkers
γ-Butylbetaine
l-Carnitine
Online Access:https://doi.org/10.1038/s41598-025-06054-1
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https://doi.org/10.1038/s41598-025-06054-1

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