PEGylated Liposomes of Disulfiram and Paclitaxel: A Promising Chemotherapeutic Combination Against Chemoresistant Breast Cancer

PEGylated Liposomes of Disulfiram and Paclitaxel: A Promising Chemotherapeutic Combination Against Chemoresistant Breast Cancer

<b>Background:</b> Steric stabilization of liposomes using PEGylation has been used widely in pharmaceutical research to overcome the limitations of conventional liposomes and to extend circulation time. PEGylation tended to improve the physicochemical stability and reverse the chemoresi...

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Bibliographic Details
Main Authors: Ammar Said Suliman, Sahrish Rehmani, Benjamin Small, Kate Butcher, Mouhamad Khoder, Vinodh Kannappan, Weiguang Wang, Abdelbary Elhissi, Mohammad Najlah
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
disulfiram
paclitaxel
PEGylated liposomes
breast tumors
cytotoxicity
chemoresistant cancer
Online Access:https://www.mdpi.com/1424-8247/18/4/487
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