An inflammation-associated lncRNA induces neuronal damage via mitochondrial dysfunction

An inflammation-associated lncRNA induces neuronal damage via mitochondrial dysfunction

Immune disease-associated non-coding SNPs, which often locate in tissue-specific regulatory elements, are emerging as key factors in gene regulation. Among these elements, long non-coding RNAs (lncRNAs) participate in many cellular processes, and their characteristics make these molecules appealing...

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Main Authors: Ane Olazagoitia-Garmendia, Henar Rojas-Márquez, Tim Trobisch, Cristina Moreno-Castro, Ariadne Rodriguez Etxebarria, Jon Mentxaka, Ajai Tripathi, Bibo Yang, Itziar Martin Ruiz, Juan Anguita, J Javier Meana, Yiliang Ding, Ranjan Dutta, Lucas Schirmer, Mariana Igoillo-Esteve, Izortze Santin, Ainara Castellanos-Rubio
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: non-coding RNAs
lncRNA
SNP
cell-specificity
RNA modification
mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253125000873
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