Silencing of interferon regulatory factor gene 6 in melanoma.

<h4>Background</h4>Methylation of a CpG island (CGI; a dense cluster of CpGs) located in the 5' region of a gene suppresses transcription of that gene. Interferon regulatory factor 6 (IRF6) is associated with the expression of interferon, which is used as an effective adjuvant thera...

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Bibliographic Details
Main Authors: Yoshimasa Nobeyama, Hidemi Nakagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184444&type=printable
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