Clostridium difficile as a potent trigger of colorectal carcinogenesis

Abstract Clostridium difficile, traditionally recognized as a cause of antibiotic-associated colitis, has emerged as a potential oncogenic factor in colorectal cancer (CRC). This article explores the mechanisms by which C. difficile toxins, TcdA and TcdB, contribute to CRC pathogenesis through epith...

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Bibliographic Details
Main Authors: Javad Nezhadi, Masoud Lahouty, Mohammad Ahangarzadeh Rezaee, Manouchehr Fadaee
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-025-02742-6
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