The Use of Design of Experiments (DoE) Approaches for the Development of Self-Emulsifying Drug Delivery Systems (SEDDS)

The Use of Design of Experiments (DoE) Approaches for the Development of Self-Emulsifying Drug Delivery Systems (SEDDS)

Self-emulsifying drug delivery systems (SEDDS) consist of isotropic mixtures of oils, surfactants, and solvents that after dispersion emulsify in the aqueous media of the gastrointestinal tract (GIT). SEDDS can deliver hydrophobic drugs, which could enhance their oral bioavailability by protecting t...

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Bibliographic Details
Main Authors: Ana Carolina Carvalho Lopes Serrano, Mateus Costa Viana, Natalha Vicentina Pinto, Eduardo Burgarelli Lages, Guilherme Carneiro, Gabriel Silva Marques Borges
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Applied Nano
Subjects:
Design of Experiments
nanomedicine
self-emulsifying drug delivery systems
Box–Behnken design
central composite design
Online Access:https://www.mdpi.com/2673-3501/6/1/4
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