Breast cancer-derived exosomal miR-105-5p facilitates the transformation of NFs into CAFs through LATS2-NF-κB signaling

Breast cancer-derived exosomal miR-105-5p facilitates the transformation of NFs into CAFs through LATS2-NF-κB signaling

Studies of cell-to-cell activities in the tumor microenvironment (TME) have identified multiple potential targets for oncotherapy. The interplay between tumor cells and neighboring cancer-associated fibroblasts (CAFs) persists in all stages...

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Bibliographic Details
Main Authors: Ding Xiaodi, Sheng Zhimei, Cui Jiayu, Cui Meimei, Zhang Liying, Feng Ruijun, Wang Yongming, Sun Wei, Zhang Xiurong, Shi Lihong, Zhang Baogang
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2025-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
breast cancer
exosomes
cancer-associated fibroblasts
tumor microenvironment
miRNAs
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2025017
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https://www.sciengine.com/doi/10.3724/abbs.2025017

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