Prospects of etiopathogenetic treatment of Huntington’s disease

Prospects of etiopathogenetic treatment of Huntington’s disease

Huntington’s disease is a serious inherited neurodegenerative disorder characterized by of motor, cognitive and psychiatric features. The disease is caused by an abnormally expanded CAG repeat expansion in the HTT gene and the production of mutant huntingtin protein.The disease usually manifests in...

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Bibliographic Details
Main Authors: O. B. Kondakova, S. V. Demyanov, A. V. Krasivskaya, G. V. Demyanov, D. I. Grebenkin, Yu. I. Davydova, A. A. Lyalina, E. R. Radkevich, K. V. Savostyanov
Format: Article
Language:Russian
Published: ABV-press 2023-03-01
Series:Нервно-мышечные болезни
Subjects:
huntington’s disease
genome editing
snp
antisense oligonucleotides
rna interference
protac
stem cells
fan1
Online Access:https://nmb.abvpress.ru/jour/article/view/523
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