Non-invasive liquid biopsy based on transcriptomic profiling for early diagnosis of occult peritoneal metastases in locally advanced gastric cancer

Non-invasive liquid biopsy based on transcriptomic profiling for early diagnosis of occult peritoneal metastases in locally advanced gastric cancer

Abstract This study proposes a novel non-invasive diagnostic approach utilizing transcriptomic profiling of liquid biopsy samples for the early detection of occult peritoneal metastases in locally advanced gastric cancer (LAGC). By analyzing RNA expression patterns of cancer cells, this method ident...

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Main Authors: Ping’an Ding, Haotian Wu, Jiaxiang Wu, Tongkun Li, Renjun Gu, Lilong Zhang, Xiaoman Niu, Jinchen He, Jiaxuan Yang, Peigang Yang, Honghai Guo, Yuan Tian, Ning Meng, Xiaolong Li, Zhenjiang Guo, Lingjiao Meng, Qun Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00875-z
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https://doi.org/10.1038/s41698-025-00875-z

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